Investigating the prevalence of dyslipidemia in different obesity groups in the Fasa cohort‎ population

1 Department of Anatomical Sciences, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran

2 Department of Tissue Engineering, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran

3 Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran

4 Vascular and endovascular surgery research center, Mashhad University of Medical Sciences, Mashhad, Iran

5 Metabolic syndrome research center, Mashhad University of Medical Sciences, Mashhad, Iran

6 Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran

Abstract

Introduction: Obesity and dyslipidemia are critical risk factors for cardiovascular diseases (CVD). ‎This study aims to assess the prevalence of dyslipidemia across various obesity categories in the adult ‎population of the Fasa cohort. ‎
Methodology: Utilizing a descriptive-analytical, cross-sectional design, the study sampled 10,118 ‎participants aged 35 to 70, categorized into eight groups based on BMI and metabolic syndrome status: ‎normal BMI, BMI 25-29.9, BMI 30-34.9, and BMI ≥35, each further divided by the presence or ‎absence of metabolic syndrome. Dyslipidemia prevalence was evaluated across these groups using chi-‎square tests and one-way ANOVA, while logistic regression analyzed the impact of each variable on ‎metabolic syndrome. Statistical significance was set at a 0.05 threshold, with SPSS software facilitating ‎data analysis. ‎
Results: The findings revealed dyslipidemia prevalence rates of 87.8% for BMI 25-29.9, 89.1% for ‎BMI 30-34.9, and 91.5% for BMI ≥35. Individuals with metabolic syndrome exhibited higher ‎dyslipidemia prevalence across all BMI groups compared to those without metabolic syndrome. ‎Additionally, the odds of having dyslipidemia in those with metabolic syndrome were 45.1% higher in ‎the BMI 25-29.9 group and 67.4% higher in the BMI 30-34.9 group than in healthy individuals. ‎
Discussion and conclusion: The high prevalence of dyslipidemia in this population underscores the ‎need for targeted policy interventions to mitigate the associated health risks and financial burdens.‎

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