The risk factors of COVID-19 in 50–74 years old people: a longitudinal population-based study


Jamali Atergeleh H, Emamian MH, Goli SH, Rohani-Rasaf M, Hashemi H,Fotouhi A
Journal of Epidemiologic Methods



To investigate the risk factors of COVID-19 infection in a longitudinal study of a population aged 50–74 years.


Data were collected from Shahroud Eye Cohort study and the COVID-19 electronic registry in Shahroud, northeast Iran. Participants were followed for about 13 months and predisposing factors for COVID-19 infection were investigated using log binominal model and calculating relative risks.


From the beginning of the COVID-19 outbreak in Shahroud (February 20, 2020) to March 26, 2021, out of 4,394 participants in the Eye Cohort study, 271 (6.1%) were diagnosed with COVID-19 with a positive reverse transcription polymerase chain reaction test on two nasopharyngeal and oropharyngeal swabs. Risk factors for COVID-19 infection included male gender (relative risk (RR) = 1.51; 95% confidence intervals (CI), 1.15–1.99), body mass index (BMI) over 25 (RR = 1.03; 95% CI, 1.01–1.05), and diabetes (RR = 1.31; 95% CI, 1.02–1.67). Also, smoking (RR = 0.51; 95% CI, 0.28–0.93) and education (RR = 0.95; 95% CI, 0.92–0.98) showed inverse associations.


Men, diabetics, and those with BMI over 25 should be more cognizant and adhere to health protocols related to COVID-19 prevention and should be given priority for vaccination.

Keywords: COVID-19; Iran; risk factors

How to Cite

Jamali Atergeleh, Hozhabr, Emamian, Mohammad Hassan, Goli, Shahrbanoo, Rohani-Rasaf, Marzieh, Hashemi, Hassan and Fotouhi, Akbar. “The risk factors of COVID-19 in 50–74 years old people: a longitudinal population-based study” Epidemiologic Methods, vol. 10, no. s1, 2021, pp. 20210024.