*Surveillance Dept. Isfahan Cardiovascular Research Center, Isfahan, Iran
Introduction: Cardiovascular diseases and stroke constitute an important cause of death in most developed and developing countries. Identification of the major risk factors of coronary accidents and stroke and understanding of the relative risk posed by each of these risk factors are critical points for prevention, control and management of this health problem.
Methods: 6542 individuals aged over 35 years from the cities of Isfahan, Arak and Najafabad were followed for two years. The individuals were chosen from among the population of 12800 people, selected in a multistage sampling manner to participate in Isfahan Healthy Heart Program (IHHP). Pregnant women, mentally retarded individuals, and those with acute systemic diseases were excluded. Risk factors were extracted based on definition, and the degree of risk posed by each risk factor was determined. Results: The incidence of acute coronary events was studied in 3970 (60.7%) healthy individuals participating in IHHP, who were followed over a two years period. 60 deaths (1.5% of the population) were reported during the two years, 1% of which were caused by myocardial infarction (MI). There were115instances of fatal and non-fatal cardiac events (2.9% of the population). Strokes were seen in half of the cases. A positive history of smoking was accompanied by reduced survival of subjects in this study. The incidence of non-fatal cardiac events also increased with diastolic hypertension and triglyceride level. In this study, the greatest risk of cardiac events was associated with hypertension, diabetes, metabolic syndrome, and positive history of smoking.
Discussion: In this study, the two-year incidence of cardiac events was higher than that of European countries. The relative risk of risk factors such as diabetes, positive history of smoking, and hypertension was also notably higher than that of similar studies. In light of the higher risk of cardiac events compared with similar studies, preparing a risk chart based on geographical and cultural features for evaluation of the risk of cardiac events seems imperative.
Author(s): Sabet Bو Derakhshan R, Sadeghi MوSarafzadegan N, Baghaei A.M., Amani A., Milani M., Derakhshan F,Hosseini SH.TWO-YEAR INCIDENCE OF ACUTE FATAL AND NON-FATAL CORONARY EVENTS AND STROKE: IRANIAN POPULATION OVER 35 YEARS OLD. ARYA ATHEROSCLEROSIS . Spring 2005 , Volume 1 , Number 1; Page(s) 9 To 14.