Associations of Opium Use with Metabolic Syndrome in Fasa PERSIAN Cohort Study: A Population-Based Study
Authors
Affiliations
- Larestan Health Center, Larestan University of Medical Sciences, Larestan, Iran.
- Department of Community Medicine, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
- Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran.
- Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
- Department of Public Health, School of Health, Khoy University of Medical Sciences, Khoy, Iran.
Abstract
Background: This study aimed to determine the relationships between opium use and metabolic syndrome in Fasa PERSIAN cohort data.
Methods: This was an analytical cross-sectional study conducted among participants of the first phase of the Fasa PERSIAN cohort study. A total of 10,074 participants (aged 35-70 years) were studied. The MetS was defined as per the National Cholesterol Education Program ATP III (NCEP-ATP III) criteria. Independent sample t-test and Chi-square test were used for univariate analysis, and multivariate logistic regression was used to control for potential confounders and calculate odds ratios (ORs).
Results: The MetS prevalence was 24.6% in the whole population (28.42% in women vs. 19.94% in men, P < 0.001). The prevalence of opium use was 23.2%. The odds of metabolic syndrome in smokers was lower than in non-smokers (OR = 1.17%, 95% CI 1.001-1.37). Conclusions: The results of this study showed that opium consumption has an inverse relationship with metabolic syndrome. However, this study was cross-sectional, and longitudinal studies are needed for more accurate conclusions. Opium is also a carcinogen. Therefore, its use is not recommended.
Keywords: Metabolic syndrome; opium; waist circumference Fasa.

