The Correlation between Intake of Vitamin C and β-Carotene and Fasting Blood Sugar: A Cross-Sectional Analysis in Diabetic Patients of Fasa Cohort Study

  1. Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  2. The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran.
  3. Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  4. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  5. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  6. Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
  7. The Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran.

Abstract

Background: Diet and nutrition are strongly implicated in the etiology of type 2 diabetes. This study has investigated whether low vitamin C and β-carotene intakes were associated with glycemic control in diabetic patients.
Methods: In a cross-sectional analysis of diabetic adult patients participating in Fasa Cohort Study, a 24-h dietary recall was used to assess intake of fruits, vegetables, vitamin C and β-carotene. The associations between vitamin C and β-carotene intakes and glycemic control were determined in 3 groups of normal glucose tolerance, pre-diabetes mellitus, and type 2 diabetes mellitus (T2DM) and the relationship between fasting blood glucose (FBS) and vitamin C and β-carotene intakes was
investigated.
Results: There were no differences between groups for intake of total vitamin C and β-carotene (p>0.05). An inverse relation was recognized between intake of total vitamin C and β-carotene and FBS (p<0.05). Conclusion: A negative association was observed between FBS and intake of vitamin C and β-carotene; however more experimental studies are needed to establish whether increase in intake of vitamin C and β-carotene can improve FBS level and prevent T2DM.

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