Mazandaran University of Medical Sciences Deputy for Research and Technology

Principal Investigators:

1) Ahmad Ali Enayati,

2) Mahmood Moosazadeh

– 1) Professor of Medical Entomology, School of Public Health, Mazandaran University of Medical Sciences, Sari, Iran,, +98-9111522209

– 2) Ph.D. in Epidemiology, Assistant professor, Health Sciences Research center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran,, +98-9113555367

24 September 2014

1 June 2015

Identifying the risk factors related to non-communicable diseases for implementation of appropriate interventions to prevent the diseases

people aged 35- 70

All resident of selected areas will be enrolled. Sample size is equal 10000.

Data will be collected using electronic questionnaire, specimens consisting Blood, urine, nail and hair samples will be collected.

Tabari cohort follow-up includes annual and periodic follow-up (re-measurement). All participants were contacted every year in order to ascertain major NCDs. The periodic follow-up will be conducted every 5 year .Among all participants, 20% will be selected randomly. They will be re-interviewed and all biological samples will be collected.

All risk factors related to chronic diseases including genetic factors, life style, socioeconomic status and environment contamination

There are three kind of outcomes of interest, including: 1. Death (confirmed cause of death), 2. Major NCDs including malignancies, cardiovascular diseases(myocardial infarction and other ischemic heart diseases, hypertension and heart failure), stroke, cerebrovascular accident, diabetes mellitus, pulmonary disease(Asthma, pneumoconiosis, COPD, chronic bronchitis and pulmonary emphysema), chronic renal failure leading to dialysis, hepatic fibrosis and cirrhosis, alzheimer and parkinson and 3.trends in risk factors or protective factors including anthropometric, physiologic, nutritional, life style, environmental and occupational factors.

Part Cohort