Mazandaran Cohort Study

Mazandaran University of Medical Sciences

Deputy for Research and Technology

Principal Investigators:

DR. Mahmood Moosazadeh

Associate Professor of Epidemiology, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences

Cohort Website 1 Cohort Website 2

Cohort study

Approval date

24 September 2014

Starting date

1 June 2015

Goals

Identifying the risk factors related to non-communicable diseases for implementation of appropriate interventions to prevent the diseases

Study population

people aged 35- 70

Sampling method and sample size

All resident of selected areas will be enrolled. Sample size is equal 10000.

Data Collection

Data will be collected using electronic questionnaire, specimens consisting Blood, urine, nail and hair samples will be collected.

Follow up Methods

Tabari cohort follow-up includes annual and periodic follow-up (re-measurement). All participants were contacted every year in order to ascertain major NCDs. The periodic follow-up will be conducted every 5 year .Among all participants, 20% will be selected randomly. They will be re-interviewed and all biological samples will be collected.

Main Exposures

All risk factors related to chronic diseases including genetic factors, life style, socioeconomic status and environment contamination

Outcomes

There are three kind of outcomes of interest, including: 1. Death (confirmed cause of death), 2. Major NCDs including malignancies, cardiovascular diseases(myocardial infarction and other ischemic heart diseases, hypertension and heart failure), stroke, cerebrovascular accident, diabetes mellitus, pulmonary disease(Asthma, pneumoconiosis, COPD, chronic bronchitis and pulmonary emphysema), chronic renal failure leading to dialysis, hepatic fibrosis and cirrhosis, alzheimer and parkinson and 3.trends in risk factors or protective factors including anthropometric, physiologic, nutritional, life style, environmental and occupational factors.