Identifying the risk factors related to non-communicable diseases for implementation of appropriate interventions to prevent the diseases
people aged 35- 70
Sampling method and sample size
All resident of selected areas will be enrolled. Sample size is equal 10000.
Data will be collected using electronic questionnaire, specimens consisting Blood, urine, nail and hair samples will be collected.
Follow up Methods
Tabari cohort follow-up includes annual and periodic follow-up (re-measurement). All participants were contacted every year in order to ascertain major NCDs. The periodic follow-up will be conducted every 5 year .Among all participants, 20% will be selected randomly. They will be re-interviewed and all biological samples will be collected.
All risk factors related to chronic diseases including genetic factors, life style, socioeconomic status and environment contamination
There are three kind of outcomes of interest, including: 1. Death (confirmed cause of death), 2. Major NCDs including malignancies, cardiovascular diseases(myocardial infarction and other ischemic heart diseases, hypertension and heart failure), stroke, cerebrovascular accident, diabetes mellitus, pulmonary disease(Asthma, pneumoconiosis, COPD, chronic bronchitis and pulmonary emphysema), chronic renal failure leading to dialysis, hepatic fibrosis and cirrhosis, alzheimer and parkinson and 3.trends in risk factors or protective factors including anthropometric, physiologic, nutritional, life style, environmental and occupational factors.