Shahid Beheshti University of Medical Sciences Safety Promotion and Injury Prevention research center
Principal Investigator: Prof. Hamid Soori
– Prof. of Epidemiology – Safety Promotion and Injury Prevention research center, School of Health and Safety, Shahid Beheshti University of Medical Sciences – 7th Floor, Build. NO 2, Safety Promotion and Injury Prevention research center, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Evin Tehran, Iran – hsoori@yahoo.com – 0098 21 22439980, 22680 4313
Approval date
1998
Starting date
1999
Goals
To study the incidence of non-communicable diseases and the association between different exposures and outcomes.
Study population
The families residing in distinct no. 13 of Tehran including all family members aged three years and above.
Sampling method and sample size
Random two-stage cluster sampling; Recruiting 15000 individuals in the first and 3500 in the second phase.
Data Collection
Interview, self-administered questionnaire, physical exam, ECG, biochemical measurements, storing serum and DNA sample.
Follow up Methods
Active fallow-up every 3 years to repeat all measurements. Up to now, 6 examinations have been conducted. – Active follow up annually for hospitalized events and death. Up to know, 18 years of follow-up have been completed.
Main Exposures
Demographic, behavioral (e.g. nutrition, physical activity and smoking), medical history, family history, biological (e.g. anthropometric, blood pressure, pulse rate), biochemical (e.g. serum levels of glucose, lipid profile and kidney, liver and thyroid function tests) and genetic factors.
Outcomes
NCDs events especially cardiovascular diseases, diabetes and other metabolic disorders and cancer. Up to Mar 2016 for any death and hospitalization and up to Mar 2017 for all measurements (Phase 6 of the TLGS) including self-reported physician diagnosis, drug history, and diagnoses based on physical exams and lab measurements, e.g. hypertension and diabetes.