Shahid Beheshti University of Medical Sciences Reproductive Endocrinology Research Center, Research Institute For Endocrine Sciences
Principal Investigator: Fahimeh Ramezani Tehrani
- -Professor of Obstetrics, Gynaecology and Reproductive Health
- -Shahid Beheshti University of Medical Sciences Director,
- -Reproductive Endocrinology Research Center,
- -Research Institute for Endocrine Sciences.
To determine Prevalence of vitamin D deficiency during pregnancy and to compare the effectiveness of different prescription methods of vitamin D3 on maternal and neonatal outcomes
All pregnant women seeking maternity care in Health Centers of Masjed-Soleyman and Shoushtar
Sampling method and sample size
First phase: Stratified, multistage probability cluster sampling method (n=2500). Second phase: Randomized clinical trial; number of sample for each group=200
Interview, questionnaire, physical exam, collecting of blood samples for assessment of serum levels of 25(OH)D.
Follow up Methods
Standard prenatal care with routine intervals.
Maternal serum vitamin D levels.
Maternal outcomes: abortion, preterm labor, Premature ruptures of membrane, preeclampsia, gestational diabetes, type of delivery Neonatal outcomes: weight, height, head circumference, icterus, convulsion, 1 and 5 minutes’ APGAR scor