Principal Investigator:
Dr. Ali Esmaeili Nadimi
Professor of Cardiology, Department of Internal Medicine, Non-Communicable Diseases Research Center, Rafsanjan University of Medical Sciences
Approval date
14/03/2016
Starting date
5/08/2015
Goals
- To investigate the risk factors of the NCDs among people aged 35-70 years
- To determine the incidence and prevalence of the NCDs and the frequency of their risk factors
- to determine the relationship between the incidence of the NCDs and some risk factors including; socioeconomic status, personal and nutritional habits, family history, hyperlipidemia, hypertension, smoking,…..and also demographic information
Study population
10,000 residents of Rafsanjan City aged 35-70 years
Sampling method and sample size
Firstly, 5 out of 8 health centers located in different parts of the city and representing total population were chosen. Secondly, 2ooo persons aged 35-70 years were randomly selected from each health center and invited for the study
Data Collection
Data on general health, personal and working life history, medical examination, the frequency, prevalence, and history of NCDs, exposure to and risk factors for NCDs, lifestyle, physical activity, and nutrition (Food Frequency Questionnaire (FFQ)) were collected by questionnaires. questionnaires of Blood, urine, hair, and nail specimens were gathered by laboratory tests
Follow up Methods
All enrolled participants would be followed for at least 10 years. During this period, participants and/ or their close relatives will receive annual phone calls. In case of any death, life-threatening conditions or of major NCDs, the local cohort team will follow the phone call with a house/hospital visit to perform a more detailed medical history, assessment and physical examinations and also to collect any related medical documents for further evaluation and recording. For the expired participants, a verbal autopsy form is also completed. 20% of the participants would be reassessed 5 years later.
Main Exposures
Occupational exposures, living conditions, and fuel status, past history of chronic diseases, family history, personal habits, physical activities, fertility history
Outcomes
Death, cardiovascular diseases particularly IHD, hypertension, and diabetes, renal failure, malignancies, any changes in risk or protective factors
Cohort Study
The study of Rafsanjan cohort has been done in order to study the future of the country in terms of health system
Gallery
RATIONALE AND DESIGN Papers
1- Hakimi H, Ahmadi J, Vakilian A, Jamalizadeh A, Kamyab Z, Mehran M, Malekzadeh R, Poustchi H, Eghtesad S, Sardari F, Soleimani M, Khademalhosseini M, Abolghasemi M, Mohammadi M, Sadeghi T, Ayoobi F, Abbasi M, Mohamadi M, Jalali Z, Shamsizadeh A, Esmaeili-Nadimi A. The profile of Rafsanjan Cohort Study. Eur J Epidemiol. 2021 Feb;36(2):243-252. doi: 10.1007/s10654-020-00668-7. Epub 2020 Jul 28. PMID: 32725579.
Questionnaires
- Nutrition
- Medical
- General
Metadata Dictionary
Staff
Ms. Mahia Mehran
Ms. Parvin Khalili
Ms. Zohreh Rajabi
Ms. Faeqeh Mohammad Akbari
Ms. Mina Jafari
Ms. Maryam Sheikh
Ms. Nahid Salimi
Ms. Atefeh Mangali
Ms. Farnaz Heidari
Ms. Nahid Karami
Mr. Mohammad Sadeghi
News
In the first phase:
10,000 people from Rafsanjan population between 35 and 70 years old have been studied.
In the second phase:
3000 people from the population will be studied