Rafsanjan University of Medical Sciences Non-communicable Diseases Research Center

Principal Investigator:



1-To investigate the risk factors of the NCDs among people aged 35-70 years 2-To determine the incidence and prevalence of the NCDs and the frequency of their risk factors 3- to determine the relationship between incidence of the NCDs and some risk factors including; socioeconomic status, personal and nutritional habits, family history, hyperlipidemia, hypertension, smoking,…..and also demographic information

10,000 residents of Rafsanjan City aged 35-70 years

Firstly, 5 out of 8 health centers located in different parts of the city and representing total population were chosen. Secondly, 2ooo persons aged 35-70 years were randomly selected from each health center and invited for the study

Data on general health, personal and working life history, medical examination, the frequency, prevalence, and history of NCDs, exposure to and risk factors for NCDs, lifestyle, physical activity, and nutrition (Food Frequency Questionnaire (FFQ)) were collected by questionnaires. questionnaires of Blood, urine, hair, and nail specimens were gathered by laboratory tests

All enrolled participants would be followed for at least 10 years. During this period, participants and/ or their close relatives will receive annual phone calls. In case of any death, life-threatening conditions or of major NCDs, the local cohort team will follow the phone call with a house/hospital visit to perform a more detailed medical history, assessment and physical examinations and also to collect any related medical documents for further evaluation and recording. For the expired participants, a verbal autopsy form is also completed. 20% of the participants would be reassessed 5 years later.

Occupational exposures, living conditions, and fuel status, past history of chronic diseases, family history, personal habits, physical activities, fertility history

Death, cardiovascular diseases particularly IHD, hypertension, and diabetes, renal failure, malignancies, any changes in risk or protective factors

Part Cohort