Dietary inflammatory index and metabolic syndrome in Iranian population (Fasa Persian Cohort Study)

  • Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
  • 2Department of Epidemiology and Biostatistics, Faculty of Health, Shahrekord University of Medical Sciences, Shahrekord, Iran.
  • 3Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran. r_homayounfar@yahoo.com.
  • 4National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. r_homayounfar@yahoo.com.
  • 5Cancer Prevention and Control Program, Arnold School of Public Health, University of South Carolina, Columbia, USA. shivappa@mailbox.sc.edu.
  • 6Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208, USA. shivappa@mailbox.sc.edu.
  • 7Connecting Health Innovations LLC, Columbia, SC, 29201, USA. shivappa@mailbox.sc.edu.
  • 8Cancer Prevention and Control Program, Arnold School of Public Health, University of South Carolina, Columbia, USA.
  • 9Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208, USA.
  • 10Connecting Health Innovations LLC, Columbia, SC, 29201, USA.
bmj open

Abstract

Metabolic syndrome (MetS) is one of the risk factors for all causes of mortality. Inflammation is an important risk factor for MetS. The present cross-sectional study aimed to investigate the relationship between MetS and pro-inflammatory diet by using the food inflammation index (DII). This study consists of 10,017 participants with an age range of 35 to 70 years. The Fasa Cohort Study (FACS) population (Fars Province, Iran) was used to collect data. The DII was estimated according to Shivappa et al. method using a validated 125-item FFQ. To determine the association between MetS components and DII Logistic regression was used (P > 0.05). The overall mean of DII was – 0.89 ± 1.74. However, adjusted multinomial logistic regression indicates each unit increase in waist circumference (WC) (OR 0.98, 95% CI 0.96-0.99) and HDL-C (OR 0.99, 95% CI 0.98-0.99) was associated with significantly decreased odds of being in the 4th DII quartile in men and all participations respectively, there is no statistically significant relationship between MetS and DII. Overall, although people in the highest quartile of inflammatory food consumption had more likely to develop MetS, this relationship was not statistically significant among males and females.

How to Cite

Ariya M, Shahraki HR, Farjam M, Ehrampoush E, Bahramali E, Homayounfar R, Shivappa N, Hebert JR. Dietary inflammatory index and metabolic syndrome in Iranian population (Fasa Persian Cohort Study). Sci Rep. 2020 Oct 7;10(1):16762. doi: 10.1038/s41598-020-73844-0. PMID: 33028906; PMCID: PMC7542151.